DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK1
Ligand Name
3-oxo-3-[(3R)-3-(pyrrolo[2,3-b][1,2,3]triazolo[4,5-d]pyridin-1(6H)-yl)piperidin-1-yl]propanenitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
COGIAVJREKAVDL-SNVBAGLBSA-N
SMILES
c1c[nH]c2c1c3c(cn2)nnn3C4CCCN(C4)C(=O)CC#N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4I5C
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Color Legend
Unassigned regionsLigand / hetero atomse4i5cA2e4i5cB1
ECOD domains from experimental PDB structures interacting with ligand C5I
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P23458n/aC5I4i5ce4i5cA2A:865-1154
P23458n/aC5I4i5ce4i5cB1B:853-1154