DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK1
Ligand Name
~{N}-[5-methyl-4-[7-[[(2~{R})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{H}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
IMKONRLYDLGQAV-MRXNPFEDSA-N
SMILES
Cc1cnc(nc1c2c[nH]c3c2cccc3NC(=O)C(C)N4CCN(CC4)C)NC(=O)C5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6GGH
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Color Legend
Unassigned regionsLigand / hetero atomse6gghA1e6gghB1
ECOD domains from experimental PDB structures interacting with ligand EYQ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P23458n/aEYQ6gghe6gghA1A:865-1154
P23458n/aEYQ6gghe6gghB1B:863-1154