[(1S)-2,2-difluorocyclopropyl][(1R,5S)-3-{2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone

P23458 — Tyrosine-protein kinase JAK1

Attributes

UniProt ID

Protein Name

Tyrosine-protein kinase JAK1

Ligand Name

[(1S)-2,2-difluorocyclopropyl][(1R,5S)-3-{2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

BUWBRTXGQRBBHG-MJBXVCDLSA-N

SMILES

Cn1cc(cn1)Nc2nccc(n2)N3CC4CCC(C3)N4C(=O)C5CC5(F)F

Drug Action

inhibitor

Affinity Metrics