DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK1
Ligand Name
1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[[4-(cyclohexen-1-yl)phenyl]methyl]-3-fluoranyl-piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JZLQNFWWJFOUEZ-YWEHKCAJSA-N
SMILES
c1cc(ccc1CN2CCC(C(C2)F)(CC#N)n3cc(c(n3)NC(=O)C4CC4)C(=O)N)C5=CCCCC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6RSB
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Color Legend
Unassigned regionsLigand / hetero atomse6rsbA1e6rsbB1
ECOD domains from experimental PDB structures interacting with ligand KGZ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P23458n/aKGZ6rsbe6rsbA1A:865-1154
P23458n/aKGZ6rsbe6rsbB1B:865-1154