DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK1
Ligand Name
1-[4-(cyanomethyl)-1-[(3-oxidanyl-4-phenyl-phenyl)methyl]piperidin-4-yl]-3-(cyclopropylcarbonylamino)pyrazole-4-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YQNPSYZTFUVTCR-UHFFFAOYSA-N
SMILES
c1ccc(cc1)c2ccc(cc2O)CN3CCC(CC3)(CC#N)n4cc(c(n4)NC(=O)C5CC5)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6RSD
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Color Legend
Unassigned regionsLigand / hetero atomse6rsdA1e6rsdB1
ECOD domains from experimental PDB structures interacting with ligand KH8
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P23458n/aKH86rsde6rsdA1A:865-1154
P23458n/aKH86rsde6rsdB1B:865-1154