DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK1
Ligand Name
methyl ~{N}-[4-aminocarbonyl-1-[(3~{R},4~{R})-4-(cyanomethyl)-1-[(4-ethenyl-2-fluoranyl-5-oxidanyl-phenyl)methyl]-3-fluoranyl-piperidin-4-yl]pyrazol-3-yl]carbamate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KNQPQNPPLBJXJR-GCJKJVERSA-N
SMILES
COC(=O)Nc1c(cn(n1)C2(CCN(CC2F)Cc3cc(c(cc3F)C=C)O)CC#N)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6RSE
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Color Legend
Unassigned regionsLigand / hetero atomse6rseA1e6rseB1
ECOD domains from experimental PDB structures interacting with ligand KHH
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P23458n/aKHH6rsee6rseA1A:865-1154
P23458n/aKHH6rsee6rseB1B:865-1154