2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE

P23921 — Ribonucleoside-diphosphate reductase large subunit

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00631

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P23921	DB00631	CFB	nD1	103.2.1	RuvA-C	ATP cone	ATP cone	ATP-cone
P23921	DB00631	CFB	nD2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
P23921	DB00631	CFB	nD3	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ribonuc_red_lgC

Show other predicted domains (64)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
2WGH	e2wghA2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e2wghB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e2wghB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e2wghA1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
3HNC	e3hncB4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hncA1	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hncB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hncA3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hncB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e3hncA2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
3HND	e3hndB4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hndA2	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hndB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hndA3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hndB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e3hndA1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
3HNE	e3hneB4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hneA1	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hneB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hneA2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hneB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e3hneA3	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
3HNF	e3hnfA3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hnfB4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e3hnfA2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hnfB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e3hnfB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e3hnfA1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
4X3V	e4x3vA4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e4x3vB4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e4x3vA3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e4x3vB3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e4x3vB2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e4x3vA2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
5D1Y	e5d1yA3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e5d1yB3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e5d1yA2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e5d1yB2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e5d1yB1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e5d1yA1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
5TUS	e5tusA4	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e5tusB3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e5tusA3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e5tusB2	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e5tusA2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e5tusB1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
6AUI	e6auiA1	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiB2	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiC3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiD2	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiE1	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiF3	103.2.1	RuvA-C	ATP cone	ATP cone	Ribonuc_red_lgN
	e6auiA3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiB1	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiC1	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiD3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiE3	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiF1	1074.1.1	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Alpha helical domain of ribonucleotide reductases	Ribonuc_red_lgN
	e6auiA2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e6auiB3	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e6auiC2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e6auiD1	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e6auiE2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like
	e6auiF2	2500.1.1	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Ten stranded beta/alpha barrel	Gly_radical,PFL-like

ECOD domains from experimental PDB structures interacting with ligand DB00631

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found