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2-[(2-azanyl-6-oxidanylidene-3,9-dihydropurin-8-yl)sulfanylmethyl]benzenecarbonitrile

P26281 — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 5RV

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 5RV

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P26281n/a5etl5RVA206e5etlA1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVA206e5etlB1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVB204e5etlA1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVB204e5etlB1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVC205e5etlC1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVC205e5etlD1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVD204e5etlC1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK
P26281n/a5etl5RVD204e5etlD1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK