DrugDomain logoDrugDomain

5'-S-[1-(2-{[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine

P26281 — 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand J1B

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand J1B

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P26281n/a3udeJ1BA171e3udeA1Alpha-beta plaits6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKHPPK