DrugDomain logoDrugDomain

(5S)-5-tert-butyl-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-3-[8-(methylsulfonyl)-1,1-dioxido-6,7,8,9-tetrahydroisothiazolo[4,5-h]isoquinolin-3-yl]-1,5-dihydro-2H-pyrrol-2-one

P26663 — Genome polyprotein

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand H5S

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand H5S

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P26663n/a3h5sH5SA571e3h5sA1helical bundle domain in reverse transcriptase-like polymeraseshelical bundle domain in reverse transcriptase-like polymeraseshelical bundle domain in reverse transcriptase-like polymerasesRdRP_3
P26663n/a3h5sH5SA571e3h5sA2Alpha-beta plaitsAdenylyl and guanylyl cyclase catalytic domain-likeAdenylyl and guanylyl cyclase catalytic domain-likeRdRP_3
P26663n/a3h5sH5SB571e3h5sB1helical bundle domain in reverse transcriptase-like polymeraseshelical bundle domain in reverse transcriptase-like polymeraseshelical bundle domain in reverse transcriptase-like polymerasesRdRP_3
P26663n/a3h5sH5SB571e3h5sB2Alpha-beta plaitsAdenylyl and guanylyl cyclase catalytic domain-likeAdenylyl and guanylyl cyclase catalytic domain-likeRdRP_3