METHOTREXATE

P26831 — Hyaluronoglucosaminidase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00563

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00563

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P26831	DB00563	7rga	MTX	A	301	e7rgaA1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	A	301	e7rgaA2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	A	301	e7rgaB1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	B	301	e7rgaA1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	B	301	e7rgaA2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	B	301	e7rgaB1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	B	301	e7rgaB2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	C	301	e7rgaC1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	C	301	e7rgaC2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	D	301	e7rgaD1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	D	301	e7rgaD2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	E	301	e7rgaE2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	E	301	e7rgaG1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	E	301	e7rgaG2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	F	301	e7rgaF1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	F	301	e7rgaF2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set
P26831	DB00563	7rga	MTX	G	301	e7rgaE1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	G	301	e7rgaG1	jelly-roll	Galactose-binding domain-like	Galactose-binding domain-like	F5_F8_type_C
P26831	DB00563	7rga	MTX	G	301	e7rgaG2	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	V-set