DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Ligand Name
2-[(1R,3S,5R,7S)-2-[4-(4-FLUOROPHENYL)PHENYL]-6-HYDROXYADAMANTAN-2-YL]-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FBTIGDUFOZJGFY-YRDUTZFVSA-N
SMILES
c1cc(ccc1c2ccc(cc2)F)C3(C4CC5CC3CC(C4)C5O)CC(=O)N6CC(C6)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5PGW
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Color Legend
Unassigned regionsLigand / hetero atomse5pgwA1e5pgwB1e5pgwD1e5pgwE1
ECOD domains from experimental PDB structures interacting with ligand 8KA
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P28845n/a8KA5pgwe5pgwA1A:26-284
P28845n/a8KA5pgwe5pgwB1B:11-286
P28845n/a8KA5pgwe5pgwD1D:11-284
P28845n/a8KA5pgwe5pgwE1E:25-284