[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate

P29317 — Ephrin type-A receptor 2

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12010

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P29317	DB12010	2RC	nD2	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	Ephrin_lbd
P29317	DB12010	2RC	nD7	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr,EphA2_TM

Show other predicted domains (117)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1MQB	e1mqbA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
1MQB	e1mqbB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2E8N	e2e8nA1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
2KSO	e2ksoA1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
2X10	e2x10A4	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e2x10A7	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e2x10A8	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e2x10A6	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e2x10A5	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
2X11	e2x11A19	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e2x11A22	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e2x11A23	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e2x11A20	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e2x11A21	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
3C8X	e3c8xA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
3CZU	e3czuA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
3FL7	e3fl7A3	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3fl7A2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e3fl7A7	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e3fl7A5	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e3fl7A6	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
3HEI	e3heiA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiC1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiE1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiG1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiI1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiK1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiM1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3heiO1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
3HPN	e3hpnA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3hpnB1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3hpnC1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3hpnD1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3hpnE1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3hpnF1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
3KKA	e3kkaC1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
	e3kkaD1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
	e3kkaE1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
3MBW	e3mbwA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3mbwA2	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e3mbwA3	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
3MX0	e3mx0A3	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3mx0C3	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e3mx0C2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e3mx0A2	11.1.1	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Immunoglobulin/Fibronectin type III/E set domains/PapD-like	Cadherin
	e3mx0A4	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
	e3mx0C4	389.1.1	EGF-like	EGF-related	EGF/Laminin	EGF
3SKJ	e3skjE1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
3SKJ	e3skjF2	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
4P2K	e4p2kA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4PDO	e4pdoA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4PDO	e4pdoB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4TRL	e4trlA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5EK7	e5ek7A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5EK7	e5ek7B1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9U	e5i9uA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9V	e5i9vA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9W	e5i9wA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9X	e5i9xA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9Y	e5i9yA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5I9Z	e5i9zA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA0	e5ia0A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ia0B1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ia0C1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA1	e5ia1A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA2	e5ia2A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA3	e5ia3A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA4	e5ia4A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5IA5	e5ia5A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NJZ	e5njzA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK0	e5nk0A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK1	e5nk1A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK2	e5nk2A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK3	e5nk3A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK4	e5nk4A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK5	e5nk5A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK6	e5nk6A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK7	e5nk7A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK8	e5nk8A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NK9	e5nk9A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKA	e5nkaA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKB	e5nkbA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKC	e5nkcA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKD	e5nkdA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKE	e5nkeA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKF	e5nkfA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKG	e5nkgA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKH	e5nkhA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NKI	e5nkiA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5NZ9	e5nz9A1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
6B9L	e6b9lA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e6b9lB1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e6b9lC1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
	e6b9lD1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6F7M	e6f7mA1	102.1.1	HhH/H2TH	SAM/DNA-glycosylase	SAM domain-like	SAM_1
6FNF	e6fnfA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6FNG	e6fngA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6FNH	e6fnhC1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6fnhA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6fnhB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HES	e6hesA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HET	e6hetA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HEU	e6heuA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HEV	e6hevA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HEW	e6hewA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HEX	e6hexA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6HEY	e6heyA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6NJZ	e6njzA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NJZ	e6njzB1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK0	e6nk0A1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK0	e6nk0B1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK1	e6nk1A1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK1	e6nk1B1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK2	e6nk2A1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NK2	e6nk2B1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NKP	e6nkpA1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)
6NKP	e6nkpB1	10.1.2	jelly-roll	Concanavalin A-like	GOLD domain-like (DEPRECATED)	APD1-4_N (DEPRECATED)

ECOD domains from experimental PDB structures interacting with ligand DB12010

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found