DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Ligand Name
(8S)-N-[(1R,2R)-2-methoxycyclobutyl]-7-(methylamino)-5-{[(1P,2'P)-2-oxo-2H-[1,2'-bipyridin]-3-yl]amino}pyrazolo[1,5-a]pyrimidine-3-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BWINBHTTZLVXGT-NVXWUHKLSA-N
SMILES
CNc1cc(nc2n1ncc2C(=O)NC3CCC3OC)NC4=CC=CN(C4=O)c5ccccn5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 8S9A
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Color Legend
Unassigned regionsLigand / hetero atomse8s9aA1e8s9aB1e8s9aC1
ECOD domains from experimental PDB structures interacting with ligand DB19278
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P29597DB19278ZSB8s9ae8s9aA1A:577-610,A:636-868
P29597DB19278ZSB8s9ae8s9aB1B:578-610,B:636-867
P29597DB19278ZSB8s9ae8s9aC1C:578-609,C:635-867