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Attributes

UniProt ID
Protein Name
Dual specificity mitogen-activated protein kinase kinase 1
Ligand Name
Trametinib
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LIRYPHYGHXZJBZ-UHFFFAOYSA-N
SMILES
CC1=C2C(=C(N(C1=O)C)Nc3ccc(cc3F)I)C(=O)N(C(=O)N2c4cccc(c4)NC(=O)C)C5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 7JUR
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Color Legend
Unassigned regionsLigand / hetero atomse7jurB1e7jurC1
ECOD domains from experimental PDB structures interacting with ligand DB08911
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P29678DB08911QOM7jure7jurC1C:41-275,C:307-381
P29678DB08911QOM7juxe7juxC1C:40-274,C:307-381