PYRUVIC ACID

P30613 — Pyruvate kinase PKLR

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00119

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P30613	DB00119	PYR	nD2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	PK

Show other predicted domains (129)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
2VGB	e2vgbA3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgbD4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgbC1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgbB3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgbA1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgbD3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgbC2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgbB2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgbA4	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgbD1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgbC3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgbB1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
2VGF	e2vgfA1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgfD4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgfC1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgfB1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgfA2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgfD2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgfC3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgfB3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgfA3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgfD1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgfC2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgfB2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
2VGG	e2vggA4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vggD1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vggC2	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vggB2	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vggA2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vggD3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vggC3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vggB3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vggA1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vggD2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vggC1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vggB1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
2VGI	e2vgiA4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgiD4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgiC1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgiB3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e2vgiA1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgiD2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgiC2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgiB1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e2vgiA3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgiD1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgiC3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e2vgiB2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
4IMA	e4imaA1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4imaD4	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4imaC1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4imaB2	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4imaA2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4imaD1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4imaC2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4imaB1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4imaA3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4imaD2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4imaC3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4imaB3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
4IP7	e4ip7A2	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4ip7D1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4ip7C3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4ip7B3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e4ip7A1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4ip7D3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4ip7C2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4ip7B2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e4ip7A3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4ip7D2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4ip7C1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e4ip7B1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
6NN4	e6nn4C1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn4A1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn4B2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn4D1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn4C2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn4A2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn4B1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn4D2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
6NN5	e6nn5A1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn5B2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn5C2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn5D1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn5A2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn5B1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn5C1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn5D2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
6NN7	e6nn7G3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn7A3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn7C3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn7E3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn7D3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn7G1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7A2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7B1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7C1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7E1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7D1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7F2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7H2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn7G2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7A1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7B2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7C2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7E2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7D2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7F1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn7H1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
6NN8	e6nn8A1	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn8B3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn8C2	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn8E3	1.1.15	cradle loop barrel	RIFT-related	PK beta-barrel domain-like	PK
	e6nn8A2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8B2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8C3	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8D2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8E2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8F2	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8G1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8H1	2002.1.1	TIM beta/alpha-barrel	TIM barrels	TIM barrels	RuBisCO_large
	e6nn8A3	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8B1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8C1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8D1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8E1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8F1	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8G2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C
	e6nn8H2	7518.1.1	PK C-terminal domain-like	PK C-terminal domain-like	PK C-terminal domain-like	PK_C

ECOD domains from experimental PDB structures interacting with ligand DB00119

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found