(8R)-8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]-5,8-dihydropyrido[4,3-d]pyrimidin-7(6H)-one
P31153 — S-adenosylmethionine synthase isoform type-2
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 7UN
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 7UN
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P31153 | n/a | 7rwg | 7UN | A | 408 | e7rwgA1 | Alpha-lytic protease prodomain-like | S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | S-AdoMet_synt_M |
| P31153 | n/a | 7rwg | 7UN | A | 408 | e7rwgA2 | Alpha-lytic protease prodomain-like | S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | S-AdoMet_synt_N |
| P31153 | n/a | 7rwg | 7UN | A | 408 | e7rwgA3 | Alpha-lytic protease prodomain-like | S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | S-AdoMet_synt_C |