Attributes
UniProt ID
Protein Name
S-adenosylmethionine synthase isoform type-2
Ligand Name
7-chloranyl-4-[(3R)-3-fluoranylpyrrolidin-1-yl]-1-phenyl-quinazolin-2-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GPTUSHRRTGGGTD-CYBMUJFWSA-N
SMILES
c1ccc(cc1)N2c3cc(ccc3C(=NC2=O)N4CCC(C4)F)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 8P4H
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Color Legend
Unassigned regionsLigand / hetero atomse8p4hA1e8p4hA2e8p4hA3e8p4hB1e8p4hB2e8p4hB3e8p4hC1e8p4hC2e8p4hC3e8p4hD1e8p4hD2e8p4hD3
ECOD domains from experimental PDB structures interacting with ligand UM6
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P31153 | n/a | UM6 | 8p4h | e8p4hA1 | A:8-125 |
| P31153 | n/a | UM6 | 8p4h | e8p4hA2 | A:252-395 |
| P31153 | n/a | UM6 | 8p4h | e8p4hA3 | A:126-251 |
| P31153 | n/a | UM6 | 8p4h | e8p4hB1 | B:126-251 |
| P31153 | n/a | UM6 | 8p4h | e8p4hB2 | B:252-395 |
| P31153 | n/a | UM6 | 8p4h | e8p4hB3 | B:15-125 |
| P31153 | n/a | UM6 | 8p4h | e8p4hC1 | C:126-251 |
| P31153 | n/a | UM6 | 8p4h | e8p4hC2 | C:252-395 |
| P31153 | n/a | UM6 | 8p4h | e8p4hC3 | C:14-125 |
| P31153 | n/a | UM6 | 8p4h | e8p4hD1 | D:9-125 |
| P31153 | n/a | UM6 | 8p4h | e8p4hD2 | D:252-395 |
| P31153 | n/a | UM6 | 8p4h | e8p4hD3 | D:126-251 |