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Attributes

UniProt ID
Protein Name
Serine hydroxymethyltransferase, mitochondrial
Ligand Name
(4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NOKJZHRLDAOFCV-NRFANRHFSA-N
SMILES
Cc1c2c([nH]n1)OC(=C(C2(c3cc(cc(c3)N4CCCC4)C(F)(F)F)C(C)C)C#N)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5V7I
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Color Legend
Unassigned regionsLigand / hetero atomse5v7iA1e5v7iA2e5v7iB1e5v7iB2
ECOD domains from experimental PDB structures interacting with ligand 8Z1
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P34897n/a8Z15v7ie5v7iA1A:345-504
P34897n/a8Z15v7ie5v7iA2A:43-344
P34897n/a8Z15v7ie5v7iB1B:345-504
P34897n/a8Z15v7ie5v7iB2B:43-344