Attributes
UniProt ID
Protein Name
Vascular endothelial growth factor receptor 2
Ligand Name
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
PHXJVRSECIGDHY-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: P35968_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD3nD4nD5nD9
ECOD domains from AlphaFold model interacting with ligand DB08901
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P35968 | DB08901 | 0LI | nD3 | 221-325 |
| P35968 | DB08901 | 0LI | nD4 | 326-420 |
| P35968 | DB08901 | 0LI | nD5 | 421-550 |
| P35968 | DB08901 | 0LI | nD9 | 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965, 996-1175, 1251-1260, 801-965,996-1175,1251-1260 |