Attributes
UniProt ID
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Ligand Name
N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JOOXLOJCABQBSG-UHFFFAOYSA-N
SMILES
Cc1cnc(nc1Nc2cccc(c2)S(=O)(=O)NC(C)(C)C)Nc3ccc(cc3)OCCN4CCCC4
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P36888_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD6nD7
ECOD domains from AlphaFold model interacting with ligand DB12500
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P36888 | DB12500 | 2TA | nD6 | 546-570 |
| P36888 | DB12500 | 2TA | nD7 | 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720, 771-970, 571-720,771-970 |