DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
von Hippel-Lindau disease tumor suppressor
Ligand Name
(2~{S},4~{R})-1-[(2~{S})-2-[(1-cyanocyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NDVQUNZCNAMROD-RZUBCFFCSA-N
SMILES
Cc1c(scn1)c2ccc(cc2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)C4(CC4)C#N)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5LLI
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Color Legend
Unassigned regionsLigand / hetero atomse5lliA1e5lliB1e5lliC1e5lliC2e5lliD1e5lliE1e5lliF1e5lliF2e5lliG1e5lliH1e5lliI1e5lliI2e5lliJ1e5lliK1e5lliL1e5lliL2
ECOD domains from experimental PDB structures interacting with ligand 6Z3
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P40337n/a6Z35llie5lliC1C:62-154
P40337n/a6Z35llie5lliF2F:62-154
P40337n/a6Z35llie5lliI2I:62-154
P40337n/a6Z35llie5lliL1L:155-204
P40337n/a6Z35llie5lliL2L:62-154