DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
von Hippel-Lindau disease tumor suppressor
Ligand Name
~{N}-[(2~{S})-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamothioyl]-4-oxidanyl-pyrrolidin-1-yl]-1-sulfanylidene-propan-2-yl]ethanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NPFDMJWSPHYAKU-VHSSKADRSA-N
SMILES
Cc1c(scn1)c2ccc(cc2)CNC(=S)C3CC(CN3C(=S)C(C)NC(=O)C)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6FMK
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Color Legend
Unassigned regionsLigand / hetero atomse6fmkA1e6fmkB1e6fmkC1e6fmkC2e6fmkD1e6fmkE1e6fmkF1e6fmkF2e6fmkG1e6fmkH1e6fmkI1e6fmkI2e6fmkJ1e6fmkK1e6fmkL1e6fmkL2
ECOD domains from experimental PDB structures interacting with ligand DV8
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P40337n/aDV86fmke6fmkC1C:62-154
P40337n/aDV86fmke6fmkF2F:62-154
P40337n/aDV86fmke6fmkI1I:62-154
P40337n/aDV86fmke6fmkL1L:155-204
P40337n/aDV86fmke6fmkL2L:62-154