~{N}-[5-[4-[2-[2-[2-[2-[3-[[3,3-dimethyl-1-[(2~{S},4~{R})-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanylidene-propoxy]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-3~{H}-pyridine-3-carboxamide
P40337 — von Hippel-Lindau disease tumor suppressor
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand Q3X
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand Q3X
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P40337 | n/a | 8bb2 | Q3X | B | 403 | e8bb2L1 | SOCS box-like | SOCS box-like | SOCS box-like | VHL_C |
| P40337 | n/a | 8bb2 | Q3X | B | 403 | e8bb2L2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8bb3 | Q3X | B | 407 | e8bb3L1 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8bb3 | Q3X | B | 407 | e8bb3L2 | SOCS box-like | SOCS box-like | SOCS box-like | VHL_C |