DrugDomain logoDrugDomain

(2~{S},4~{R})-~{N}-[(1~{S})-3-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethylamino]-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-3-oxidanylidene-propyl]-1-[(2~{R})-3-methyl-2-(3-methyl-1,2-oxazol-5-yl)butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide

P40337 — von Hippel-Lindau disease tumor suppressor

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand QLX

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand QLX

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P40337n/a8bdtQLXD301e8bdtD1Immunoglobulin-like beta-sandwichImmunoglobulin-relatedPrealbumin-likeVHL
P40337n/a8bdtQLXH301e8bdtH2Immunoglobulin-like beta-sandwichImmunoglobulin-relatedPrealbumin-likeVHL