N-{3-[1-(4-{[3-(cyclopropylamino)-3-oxopropyl](methyl)amino}-6-{methyl[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]amino}-1,3,5-triazin-2-yl)piperidin-4-yl]propanoyl}-3-methyl-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide
P40337 — von Hippel-Lindau disease tumor suppressor
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand X5K
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand X5K
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P40337 | n/a | 8ewv | X5K | C | 501 | e8ewvC2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | G | 501 | e8ewvG2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | K | 501 | e8ewvK2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | O | 501 | e8ewvO2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | S | 501 | e8ewvS2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | W | 501 | e8ewvG1 | SOCS box-like | SOCS box-like | SOCS box-like | VHL_C |
| P40337 | n/a | 8ewv | X5K | W | 501 | e8ewvG2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |
| P40337 | n/a | 8ewv | X5K | W | 501 | e8ewvW2 | Immunoglobulin-like beta-sandwich | Immunoglobulin-related | Prealbumin-like | VHL |