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Buprenorphine

P41145 — Kappa-type opioid receptor

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Attributes

UniProt ID
P41145
Protein Name
Kappa-type opioid receptor
Ligand Name
Buprenorphine
DrugBank ID
DB00921
PDB Ligand Accession
n/a
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
n/a
SMILES
CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1CC4=C5C(O[C@@H]2[C@@]35CCN1CC1CC1)=C(O)C=C4
Drug Action
antagonist
Affinity Metrics
ki:0.04 nM
ic50:1.2 nM
ec50:0.18 nM