METHOTREXATE
P41440 — Reduced folate transporter
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB00563
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB00563
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P41440 | DB00563 | 7tx6 | MTX | A | 2644 | e7tx6A1 | Major facilitator superfamily (MFS) general substrate transporter | Major facilitator superfamily (MFS) general substrate transporter | Major facilitator superfamily (MFS) general substrate transporter | Folate_carrier |
| P41440 | DB00563 | 7tx6 | MTX | A | 2644 | e7tx6A2 | Major facilitator superfamily (MFS) general substrate transporter | Major facilitator superfamily (MFS) general substrate transporter | Major facilitator superfamily (MFS) general substrate transporter | Folate_carrier |