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Attributes

UniProt ID
Protein Name
Signal transducer and activator of transcription 5A
Ligand Name
N-{5-[difluoro(phosphono)methyl]-1-benzothiophene-2-carbonyl}-3-methyl-L-valyl-L-prolyl-N-(5-{2-[(3R)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}pent-4-yn-1-yl)-N-methyl-N~3~-[4-(1,3-thiazol-2-yl)phenyl]-beta-alaninamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LOPYPDQOHNOVBM-JUDNIGJXSA-N
SMILES
CC(C)(C)C(C(=O)N1CCCC1C(=O)N(CCC(=O)N(C)CCCC#Cc2cccc3c2CN(C3=O)C4CCC(=O)NC4=O)c5ccc(cc5)c6nccs6)NC(=O)c7cc8cc(ccc8s7)C(F)(F)P(=O)(O)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 7TVA
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Color Legend
Unassigned regionsLigand / hetero atomse7tvaA1e7tvaA2e7tvaA3e7tvaA4e7tvaB1e7tvaB2e7tvaB3e7tvaB4
ECOD domains from experimental PDB structures interacting with ligand KOO
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P42229n/aKOO7tvae7tvaA2A:471-584
P42229n/aKOO7tvae7tvaA4A:585-699
P42229n/aKOO7tvae7tvaB3B:585-699