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Attributes

UniProt ID
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Ligand Name
(2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
STUWGJZDJHPWGZ-LBPRGKRZSA-N
SMILES
Cc1c(sc(n1)NC(=O)N2CCCC2C(=O)N)c3ccnc(c3)C(C)(C)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4JPS
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Color Legend
Unassigned regionsLigand / hetero atomse4jpsA1e4jpsA2e4jpsA3e4jpsA4e4jpsA5e4jpsB2e4jpsB3
ECOD domains from experimental PDB structures interacting with ligand DB12015
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P42336DB120151LT4jpse4jpsA1A:697-1061
P42336DB120151LT7myoe7myoA1A:695-1050
P42336DB120151LT7pg6e7pg6A2A:697-1065
P42336DB120151LT8guae8guaA4A:698-1050
P42336DB120151LT8gube8gubA4A:697-1050
P42336DB120151LT8gude8gudA2A:698-1050