DrugDomain logoDrugDomain

4-(difluoromethyl)-5-{4-[(3S)-3-methylmorpholin-4-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}pyridin-2-amine

P42336 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand M1J

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand M1J

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P42336n/a6oacM1JA1101e6oacA3Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase