1-[7-[[2-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone
P42336 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand QIH
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand QIH
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P42336 | n/a | 8ow2 | QIH | A | 1101 | e8ow2A1 | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase/SAICAR synthase/ATP-grasp | Protein kinase | PI3_PI4_kinase |
| P42336 | n/a | 8ow2 | QIH | A | 1101 | e8ow2A3 | Immunoglobulin-like beta-sandwich | C2 domain | C2 domain | PI3K_C2 |
| P42336 | n/a | 8ow2 | QIH | A | 1101 | e8ow2A4 | Repetitive alpha hairpins | ARM repeat | ARM repeat | PI3Ka |