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2,2-difluoroethyl (3S)-3-{[2'-amino-5-fluoro-2-(morpholin-4-yl)[4,5'-bipyrimidin]-6-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate

P42336 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand VXY

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand VXY

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P42336n/a7k6mVXYA9001e7k6mA3Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase