DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Ligand Name
N~2~-{(4S,11aP)-2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-L-alaninamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SGEUNORSOZVTOL-CABZTGNLSA-N
SMILES
CC(C(=O)N)Nc1ccc-2c(c1)OCCn3c2nc(c3)N4C(COC4=O)C(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 8EXV
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Color Legend
Unassigned regionsLigand / hetero atomse8exvA1e8exvA2e8exvA3e8exvA4
ECOD domains from experimental PDB structures interacting with ligand DB15275
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P42336DB15275X3N8exve8exvA1A:698-1051
P42336DB15275X3N8tdue8tduA4A:697-1061
P42336DB15275X3N8tdue8tduC5C:697-1061
P42336DB15275X3N8tgde8tgdA4A:697-1063
P42336DB15275X3N8tgde8tgdC4C:697-1061