DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Ligand Name
N-{(3R,6M)-3-(2-chloro-5-fluorophenyl)-6-[(4S)-5-cyano[1,2,4]triazolo[1,5-a]pyridin-6-yl]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}-3-fluoro-5-(trifluoromethyl)benzamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VYWRYBZVVSPTQN-SANMLTNESA-N
SMILES
c1cc(c(cc1F)C2c3c(cc(cc3NC(=O)c4cc(cc(c4)F)C(F)(F)F)c5ccc6ncnn6c5C#N)C(=O)N2)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 8TSD
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse8tsdA1e8tsdA2e8tsdA3e8tsdA4e8tsdA5e8tsdB1e8tsdB2
ECOD domains from experimental PDB structures interacting with ligand XUZ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P42336n/aXUZ8tsde8tsdA5A:697-1049