DrugDomain logoDrugDomain

N-(2-aminopyrimidin-5-yl)-N'-[(1R)-1-(5,7-difluoro-3-methyl-1-benzofuran-2-yl)-2,2,2-trifluoroethyl]urea

P42336 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand ZWE

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand ZWE

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P42336n/a8tduZWEA1102e8tduA4Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336n/a8tduZWEC1102e8tduC5Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336n/a8tgdZWEA1512e8tgdA4Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336n/a8tgdZWEC1505e8tgdC4Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase