Attributes
UniProt ID
Protein Name
Serine/threonine-protein kinase mTOR
Ligand Name
[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES
CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)(O)O)C
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P42345_F1
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomsnD2nD5nD7nD8
ECOD domains from AlphaFold model interacting with ligand DB12010
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P42345 | DB12010 | 2RC | nD2 | 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320,361-1250 |
| P42345 | DB12010 | 2RC | nD5 | 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830,1871-2020 |
| P42345 | DB12010 | 2RC | nD7 | 2021-2115 |
| P42345 | DB12010 | 2RC | nD8 | 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445,2476-2549 |