Attributes
UniProt ID
Protein Name
Serine/threonine-protein kinase mTOR
Ligand Name
(1R,2R,4S)-4-{(2R)-2-[(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30S,34aS)-9,27-dihydroxy-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-1,5,11,28,29-pentaoxo-1,4,5,6,9,10,11,12,13,14,21,22,23,24,25,26,27,28,29,31,32,33,34,34a-tetracosahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontin-3-yl]propyl}-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
CBPNZQVSJQDFBE-FUXHJELOSA-N
SMILES
CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: P42345_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD2nD5nD7nD8
ECOD domains from AlphaFold model interacting with ligand DB06287
| UniProt | DrugBank | PDB Ligand | ECOD Domain | Range Definition |
|---|---|---|---|---|
| P42345 | DB06287 | A4I | nD2 | 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320, 361-1250, 276-320,361-1250 |
| P42345 | DB06287 | A4I | nD5 | 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830, 1871-2020, 1681-1830,1871-2020 |
| P42345 | DB06287 | A4I | nD7 | 2021-2115 |
| P42345 | DB06287 | A4I | nD8 | 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445, 2476-2549, 2116-2445,2476-2549 |