RAPAMYCIN IMMUNOSUPPRESSANT DRUG

P42345 — Serine/threonine-protein kinase mTOR

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00877

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00877

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P42345	DB00877	1fap	RAP	A	108	e1fapB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4drh	RAP	A	201	e4drhB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4drh	RAP	A	201	e4drhE1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4drh	RAP	D	201	e4drhB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4drh	RAP	D	201	e4drhE1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4dri	RAP	A	201	e4driB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	4drj	RAP	A	201	e4drjB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	5flc	RAP	C	999	e5flcB2	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	5flc	RAP	G	999	e5flcF3	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	5gpg	RAP	A	301	e5gpgB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4u	RAP	A	201	e6m4uB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4u	RAP	A	201	e6m4uF1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4u	RAP	E	201	e6m4uB1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4u	RAP	E	201	e6m4uF1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4w	RAP	D	201	e6m4wG1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4w	RAP	E	201	e6m4wH1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom
P42345	DB00877	6m4w	RAP	F	201	e6m4wI1	Four-helical up-and-down bundle	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	FRB_dom