~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{S})-6-chloranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-[5-fluoranyl-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide
P43235 — Cathepsin K
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand J5T
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand J5T
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P43235 | n/a | 6qlw | J5T | A | 301 | e6qlwA1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Peptidase_C1 |
| P43235 | n/a | 6qlw | J5T | B | 301 | e6qlwB1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Peptidase_C1 |
| P43235 | n/a | 6qlw | J5T | C | 301 | e6qlwC1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Peptidase_C1 |
| P43235 | n/a | 6qlw | J5T | D | 301 | e6qlwD1 | Cysteine proteinases-like | Cysteine proteinases | Cysteine proteinases | Peptidase_C1 |