DrugDomain logoDrugDomain

3-[6-({4-[ethyl(1H-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1H-indazol-1-yl]propan-1-ol

P43405 — Tyrosine-protein kinase SYK

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 4DT

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 4DT

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P43405n/a4yjv4DTA701e4yjvA1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr