DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase SYK
Ligand Name
4-{[5-fluoro-4-(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}-4-methyl-1H-pyrrol-1-yl)pyrimidin-2-yl]amino}-2,6-dimethylphenyl methanesulfonate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
JEDIVKVRGQEZRX-LJQANCHMSA-N
SMILES
Cc1cc(cc(c1OS(=O)(=O)C)C)Nc2ncc(c(n2)n3cc(c(c3)CN4CCC(C4)O)C)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4XG3
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Color Legend
Unassigned regionsLigand / hetero atomse4xg3A1e4xg3B1
ECOD domains from experimental PDB structures interacting with ligand X3G
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P43405n/aX3G4xg3e4xg3A1A:363-634
P43405n/aX3G4xg3e4xg3B1B:363-633