Attributes
UniProt ID
Protein Name
Nicotinamide phosphoribosyltransferase
Ligand Name
N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-6-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XRDVXQQZLHVEQZ-UHFFFAOYSA-N
SMILES
c1cc(ccc1CNC(=O)c2ccc3nccn3c2)S(=O)(=O)c4cc(cc(c4)F)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4KFO
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Color Legend
Unassigned regionsLigand / hetero atomse4kfoA1e4kfoA2e4kfoA3e4kfoB1e4kfoB2e4kfoB3
ECOD domains from experimental PDB structures interacting with ligand 1QS
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P43490 | n/a | 1QS | 4kfo | e4kfoA1 | A:162-391 |
| P43490 | n/a | 1QS | 4kfo | e4kfoA3 | A:8-161,A:392-427 |
| P43490 | n/a | 1QS | 4kfo | e4kfoB1 | B:162-391 |
| P43490 | n/a | 1QS | 4kfo | e4kfoB2 | B:8-161,B:392-427 |
| P43490 | n/a | 1QS | 4o28 | e4o28A1 | A:8-161,A:392-427 |
| P43490 | n/a | 1QS | 4o28 | e4o28A2 | A:162-391 |
| P43490 | n/a | 1QS | 4o28 | e4o28B1 | B:8-161,B:392-427 |
| P43490 | n/a | 1QS | 4o28 | e4o28B3 | B:162-391 |