N-(4-{[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]sulfonyl}benzyl)-2H-pyrrolo[3,4-c]pyridine-2-carboxamide
P43490 — Nicotinamide phosphoribosyltransferase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 1R7
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 1R7
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P43490 | n/a | 4kfp | 1R7 | A | 601 | e4kfpA1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 4kfp | 1R7 | A | 601 | e4kfpB2 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 4kfp | 1R7 | B | 601 | e4kfpA1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 4kfp | 1R7 | B | 601 | e4kfpA2 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 4kfp | 1R7 | B | 601 | e4kfpB3 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |