1-(5-O-phosphono-beta-D-ribofuranosyl)-N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
P43490 — Nicotinamide phosphoribosyltransferase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 20T
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 20T
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P43490 | n/a | 4m6q | 20T | A | 601 | e4m6qA2 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 4m6q | 20T | A | 601 | e4m6qB3 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 4m6q | 20T | B | 601 | e4m6qA1 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 4m6q | 20T | B | 601 | e4m6qA2 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 4m6q | 20T | B | 601 | e4m6qB1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |