Attributes
UniProt ID
Protein Name
Nicotinamide phosphoribosyltransferase
Ligand Name
N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LKBHAGGICJWHQQ-UHFFFAOYSA-N
SMILES
c1cc(cc(c1)S(=O)(=O)c2ccc(cc2)CNC(=O)c3cc4c[nH]nc4nc3)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4O13
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Color Legend
Unassigned regionsLigand / hetero atomse4o13A1e4o13A2e4o13A3e4o13B1e4o13B2e4o13B3
ECOD domains from experimental PDB structures interacting with ligand 2P1
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P43490 | n/a | 2P1 | 4o13 | e4o13A2 | A:162-391 |
| P43490 | n/a | 2P1 | 4o13 | e4o13A3 | A:8-161,A:392-427 |
| P43490 | n/a | 2P1 | 4o13 | e4o13B1 | B:162-391 |
| P43490 | n/a | 2P1 | 4o13 | e4o13B2 | B:8-161,B:392-427 |
| P43490 | n/a | 2P1 | 4o15 | e4o15A1 | A:8-161,A:392-427 |
| P43490 | n/a | 2P1 | 4o15 | e4o15A2 | A:162-391 |
| P43490 | n/a | 2P1 | 4o15 | e4o15B1 | B:8-161,B:392-427 |
| P43490 | n/a | 2P1 | 4o15 | e4o15B2 | B:162-391 |