DrugDomain logoDrugDomain

N-[4-[(4R)-4-methyl-1-(oxan-4-yl)-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide

P43490 — Nicotinamide phosphoribosyltransferase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 7YK

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 7YK

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P43490n/a7ppe7YKA502e7ppeA1TIM beta/alpha-barrelNicotinate/Quinolinate PRTase C-terminal domain-likeNicotinate/Quinolinate PRTase C-terminal domain-likeNAPRTase
P43490n/a7ppe7YKA502e7ppeB3alpha/beta-Hammerhead/Barrel-sandwich hybridalpha/beta-Hammerhead/Barrel-sandwich hybridNicotinate/Quinolinate PRTase N-terminal domain-likeNAPRTase,NAMPT_N
P43490n/a7ppe7YKB502e7ppeA1TIM beta/alpha-barrelNicotinate/Quinolinate PRTase C-terminal domain-likeNicotinate/Quinolinate PRTase C-terminal domain-likeNAPRTase
P43490n/a7ppe7YKB502e7ppeA2alpha/beta-Hammerhead/Barrel-sandwich hybridalpha/beta-Hammerhead/Barrel-sandwich hybridNicotinate/Quinolinate PRTase N-terminal domain-likeNAMPT_N
P43490n/a7ppe7YKB502e7ppeB2TIM beta/alpha-barrelTIM barrelsTIM barrelsNAPRTase