N-[4-[(4R)-1-cyclopentyl-4-methyl-6-oxidanylidene-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide

P43490 — Nicotinamide phosphoribosyltransferase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 7YX

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 7YX

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P43490	n/a	7ppg	7YX	A	503	e7ppgA1	TIM beta/alpha-barrel	Nicotinate/Quinolinate PRTase C-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	NAPRTase
P43490	n/a	7ppg	7YX	A	503	e7ppgB1	alpha/beta-Hammerhead/Barrel-sandwich hybrid	alpha/beta-Hammerhead/Barrel-sandwich hybrid	Nicotinate/Quinolinate PRTase N-terminal domain-like	NAMPT_N
P43490	n/a	7ppg	7YX	B	503	e7ppgA1	TIM beta/alpha-barrel	Nicotinate/Quinolinate PRTase C-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	NAPRTase
P43490	n/a	7ppg	7YX	B	503	e7ppgA2	alpha/beta-Hammerhead/Barrel-sandwich hybrid	alpha/beta-Hammerhead/Barrel-sandwich hybrid	Nicotinate/Quinolinate PRTase N-terminal domain-like	NAMPT_N
P43490	n/a	7ppg	7YX	B	503	e7ppgB2	TIM beta/alpha-barrel	Nicotinate/Quinolinate PRTase C-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	NAPRTase
P43490	n/a	7ppg	7YX	C	503	e7ppgC1	TIM beta/alpha-barrel	Nicotinate/Quinolinate PRTase C-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	NAPRTase
P43490	n/a	7ppg	7YX	C	503	e7ppgD2	alpha/beta-Hammerhead/Barrel-sandwich hybrid	alpha/beta-Hammerhead/Barrel-sandwich hybrid	Nicotinate/Quinolinate PRTase N-terminal domain-like	NAMPT_N
P43490	n/a	7ppg	7YX	D	504	e7ppgC2	alpha/beta-Hammerhead/Barrel-sandwich hybrid	alpha/beta-Hammerhead/Barrel-sandwich hybrid	Nicotinate/Quinolinate PRTase N-terminal domain-like	NAMPT_N
P43490	n/a	7ppg	7YX	D	504	e7ppgD1	TIM beta/alpha-barrel	Nicotinate/Quinolinate PRTase C-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	NAPRTase