DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Nicotinamide phosphoribosyltransferase
Ligand Name
N-[4-[(5R)-1-(4-azanylbutyl)-6-oxidanylidene-5-quinolin-5-yl-4,5-dihydropyridazin-3-yl]phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NJFRNKQNKJTDFZ-HHHXNRCGSA-N
SMILES
c1cc(c2cccnc2c1)C3CC(=NN(C3=O)CCCCN)c4ccc(cc4)NC(=O)N5Cc6ccncc6C5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 7PPI
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse7ppiA1e7ppiA2e7ppiA3e7ppiB1e7ppiB2e7ppiB3e7ppiC1e7ppiC2e7ppiD1e7ppiD2e7ppiD3
ECOD domains from experimental PDB structures interacting with ligand 7Z2
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P43490n/a7Z27ppie7ppiA2A:9-161,A:392-427
P43490n/a7Z27ppie7ppiA3A:162-391
P43490n/a7Z27ppie7ppiB1B:9-161,B:392-427
P43490n/a7Z27ppie7ppiB2B:162-391
P43490n/a7Z27ppie7ppiC1C:9-160
P43490n/a7Z27ppie7ppiC2C:161-484
P43490n/a7Z27ppie7ppiD1D:9-161,D:392-427
P43490n/a7Z27ppie7ppiD2D:162-391