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Attributes

UniProt ID
Protein Name
Nicotinamide phosphoribosyltransferase
Ligand Name
5-fluoro-N-{4-[1-(2-hydroxy-2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-isoindole-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XZCZXZPDNUPSAB-UHFFFAOYSA-N
SMILES
CC(C)(C(=O)N1CCC(CC1)c2ccc(cc2)NC(=O)n3cc4ccc(cc4c3)F)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5UPF
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Color Legend
Unassigned regionsLigand / hetero atomse5upfA1e5upfA2e5upfB1e5upfB2
ECOD domains from experimental PDB structures interacting with ligand 8HV
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P43490n/a8HV5upfe5upfA1A:161-484
P43490n/a8HV5upfe5upfA2A:9-160
P43490n/a8HV5upfe5upfB1B:9-160
P43490n/a8HV5upfe5upfB2B:161-484